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Washington — The Federal Reserve sounded a note of concern Wednesday about how global pressures could affect the U.S. economy, while keeping a key interest rate unchanged.

Six weeks after it raised rates from record lows, the Fed took stock of a more perilous international picture that could alter its plans for further raising rates. The statement it issued after its latest policy meeting signaled that it might consider slowing future rate hikes if market losses and global weakness don’t abate.

But the Fed did not commit to slowing its pace of rate increases, and stock investors appeared disappointed. The Dow Jones industrial average closed down about 223 points, or 1.4 percent. The Dow had been up slightly before the Fed issued its statement.

Sam Stovall, U.S. equity strategist at S&P Capital IQ, said investors had been hoping for a “clear signal” that the Fed would raise rates more gradually for the rest of 2016 and felt discouraged when they didn’t get it.

Many point to the Fed’s December rate hike as a key factor in the stock market’s recent tumble. The move amounted to only a small rise in the Fed’s still-extremely-low target rate for overnight bank lending. But it signaled that a seven-year period of near-zero rates was ending and that borrowing costs would rise, if not quickly.

The Fed’s new statement said it’s studying “global economic and financial developments and is assessing their implications for the labor market and inflation.”

“This is intended to lull us into lower expectations as to when the next move is going to come,” said Patrick O’Keefe, director of economic research at the consulting firm CohnReznick.

Since the Fed raised rates Dec. 16, stocks have plunged, oil prices have skidded and China’s leaders have struggled to manage a slowdown in the world’s second-biggest economy. The Fed’s statement Wednesday noted U.S. economic growth has also slowed.

Some economists say they now expect just two modest Fed rate increases during 2016, rather than the three or four they had foreseen when the year began. But no one is sure.

The Fed’s signal in December that it would raise rates four times this year “has become less plausible,” O’Keefe said. “Reality has refused to cooperate.”

In a key change to the statement, the Fed dropped language it had used in December that it was “reasonably confident” inflation would reach the Fed’s 2 percent target in the next few years.

By dropping this language, the Fed appeared to signal concern that inflation has fallen further as a result of a further drop in oil prices and a stronger dollar. Chairwoman Janet Yellen and other Fed officials have stressed the importance of higher inflation. A key inflation gauge has run below the 2 percent target for more than three years.

The Fed’s policymakers left their benchmark rate unchanged in a range of 0.25 percent to 0.5 percent. For seven years until December, they had kept that rate at record lows near zero.

“It was very noncommittal,” Asha Bangalore, economist at Northern Trust, said of the Fed’s statement.

Still, the changes the Fed made in describing economic conditions signaled that it might be prepared to slow its credit tightening until it sees more evidence that the markets and the economy are stabilizing.

The December statement had said the economy was expanding at a “moderate pace.” The new statement notes that “growth slowed late last year.”

The previous statement also described risks to the outlook as “balanced.” That description was dropped Wednesday. In its place, the Fed inserted its concern about global economic and financial developments.

The Fed’s statement was approved by a vote of 10-0.

In the first three trading weeks of 2016, the Dow shed more than 7 percent of its value. China has unnerved investors because of an economic slowdown that Beijing seems incapable of steering properly. That country’s decelerating growth has shrunk global commodity prices and the emerging market countries that have supplied them to China.

The tumbling markets have yet to rattle consumers. One measurement of confidence rose for a second month, the Conference Board said this week. Much of the optimism stems from solid job growth: U.S. employers added an average of 284,000 jobs a month in the final quarter of last year. And the unemployment rate remains a low 5 percent. Home and auto sales have also been solid.

But American manufacturing has remained weak. Export sales have slowed in part because a higher-valued dollar has made goods more expensive overseas. The strong dollar has also made imports cheaper and helped hold down inflation.

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