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New York — Anne Jackson, a Tony Award-nominated theater actress who often appeared onstage with her husband, Eli Wallach, in comedies and classics, has died. She was 90.

Peter Wallach says his mother died Tuesday morning at her home in Manhattan of natural causes.

Jackson and Wallach were a formidable duo onstage, starring in a series of plays, including George Bernard Shaw’s “Major Barbara” in 1956 and a hugely successful run of “Luv,” directed by Mike Nichols, in the mid-1960s.

Their partnership was epic by Hollywood acting-couple standards. They played a married couple together as recently as 2003 on the NBC medical drama “ER.”

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