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Los Angeles — Kevin Hogan passed for 279 yards and two touchdowns, Remound Wright rushed for three more scores and Stanford opened Pac-12 play with a 41-31 victory over No. 6 Southern California on Saturday night.

Austin Hooper and Devon Cajuste caught touchdown passes as Hogan finally beat USC for the first time in his career, snapping the Trojans’ two-game winning streak in this lively in-state rivalry.

Christian McCaffrey rushed for 115 yards for the Cardinal (2-1, 1-0), who scored just six points in their stunning season-opening loss at Northwestern. Stanford looked more like its usual powerhouse self Saturday during a 474-yard offensive performance at the Coliseum, where it has won four times in the last five trips.

Cody Kessler was 25-of-32 for 272 yards and three touchdowns, but USC (2-1, 0-1) couldn’t match the steady production of Hogan, who went 18-for-23, and his dominant offensive line.

Steven Mitchell Jr. caught two touchdown passes and JuJu Smith-Schuster caught another, but preseason Pac-12 favorite USC failed its first test of the season after beating two Sun Belt opponents by a combined 99 points earlier this month.

After USC’s impressive start, Stanford took a 24-21 halftime lead with two touchdowns in the final 3:53. Wright’s third TD run put the Cardinal up 38-28 with 11:21 to play, and Conrad Ukropina hit a 46-yard field goal with 2:27 left, essentially sealing Stanford’s sixth win over USC in their last nine meetings.

Stanford and USC began their football meetings in 1905, but the past several years of the rivalry have been particularly memorable.

The Cardinal stunned then-No. 2 USC as a 41-point underdog at the Coliseum in 2007, and Andrew Luck’s team won a triple-overtime thriller here four years ago. The Trojans won the past two meetings on last-minute field goals by Andre Heidari, including an eventful 13-10 victory at Stanford last season.

Hogan didn’t excel in either of his first two clashes with Kessler and USC, which largely relied on its defense to beat Stanford twice. Hogan and Kessler both were in elite form for this meeting, but Stanford’s offensive line largely made the difference against USC’s defense.

USC won the opening coin toss and ran the ball right at the Cardinal, going 76 yards on a methodical opening drive capped by Tre Madden’s 5-yard TD run.

Stanford played without two key contributors on its injury-plagued defensive line, leaving the Cardinal with no tested depth behind its three starters. USC rarely had trouble moving the ball, but hurt itself with eight penalties and didn’t get many drives, thanks to Stanford’s clock-chewing offense.

Hogan and his teammates quickly found the groove they missed in their first two games. The senior quarterback had plenty of time to pick apart USC’s secondary for 221 yards passing in the first half, including Hooper’s 16-yard TD catch late in the first half.

Smith-Schuster put the Trojans up 21-10 with a 54-yard catch-and-run TD in the second quarter, but Stanford scored twice in the final 3:53 of the first half. Cajuste put the Cardinal up 24-21 with 3 seconds left with a 17-yard TD catch when Adoree Jackson fell down.

Jackson also had an early 97-yard kickoff return for a touchdown erased by a penalty.

No. 3 TCU 56, (at) SMU 37: Trevone Boykin threw for 454 yards and five touchdowns for the Horned Frogs and added a highlight scoring run when he ducked out of a sack.

TCU (3-0) won its 11th consecutive game, a winning streak second only to the 16 in a row by top-ranked defending national champion Ohio State.

TCU was up 42-17 when Boykin threw a 31-yard TD pass to Kolby Listenbee on the first series after halftime. But SMU, with its own dual-threat quarterback in Matt Davis, scored the next 20 points before Boykin’s 42-yard scoring strike to Josh Doctson with 6:32 left.

Boykin, who finished fourth in the Heisman Trophy voting last year, completed 21 of 30 passes. His only interception did help the late surge by SMU (1-2), but the senior quarterback made another big throw to Doctson to make sure the Frogs avoided being upset in the Battle for the Iron Skillet.

Doctson had five catches for 171 yards and two touchdowns. Aaron Green ran 21 times for 164 yards with two scores, including a 1-yarder in the final minute.

(At) No. 7 Georgia 52, South Carolina 20: Greyson Lambert answered his skeptics with a near-perfect performance, throwing for 330 yards and three touchdowns and setting an NCAA record by completing all but one of his 25 passes to lead the Bulldogs.

Lambert posted the highest percentage (96.0) in FBS history for a minimum of 20 completions, breaking the mark of 95.8 (23 of 24) shared by Tennessee’s Tee Martin and West Virginia’s Geno Smith. Lambert also completed his final 20 passes, breaking the previous school record of 19 straight completions by Mike Bobo in the 1998 Outback Bowl.

Nick Chubb eclipsed 100 yards rushing for the 11th game in a row, carrying 21 times for 159 yards and two scores. Sony Michel ran for a TD and had two more receiving.

Georgia (3-0, 2-0 Southeastern Conference) seized control with a touchdown in the final seconds of the first half and two more in the first 2-1/2 minutes of the third quarter, taking advantage of an interception by South Carolina’s new starting quarterback, former walk-on Perry Orth.

South Carolina (1-2, 0-2) has lost its first two conference games for the first time since 2008. It was the most points a Steve Spurrier-coached team has ever given up to Georgia.

(At) No. 10 UCLA 24, No. 19 BYU 23: Nate Starks scored on a 3-yard run with 3:25 remaining and Paul Perkins rushed for 219 yards and a touchdown as UCLA rallied.

With freshman quarterback Josh Rosen struggling, the Bruins' ground game picked up the slack to maintain coach Jim Mora's perfect regular-season record against non-conference opponents.

Starks ripped off runs of 31 and 22 yards on consecutive carries before scoring two plays later, finishing with 81 yards for UCLA (3-0).

(At) No. 12 Oregon 61, Georgia State 28: Jeff Lockie threw for 228 yards and two touchdowns in his first start for the Ducks.

Lockie replaced Vernon Adams, who was rested with a broken index finger on his throwing hand.

Royce Freeman ran for 101 yards and a touchdown to help Oregon (2-1) rebound from a loss at Michigan State. Aidan Schneider added four field goals, all in the first half as the Ducks built a 33-7 lead.

Nick Arbuckle threw for 318 yards and three touchdowns, and freshman Penny Hart had nine catches for 128 yards for the Panthers (1-2).

(At) No. 13 LSU 45, No. 18 Auburn 21: Leonard Fournette ran for a career-high 228 yards and three touchdowns for the Tigers.

Fournette gained 71 yards on LSU’s first play from scrimmage and had 169 yards by halftime, then was rested for much of the second half — perhaps the only thing preventing him from breaking Alley Broussard’s single-game LSU rushing record of 250 yards, set against Mississippi in 2004.

LSU (2-0, 2-0 Southeastern Conference), finished with 411 yards on the ground. Quarterback Brandon Harris added 66 yards and two touchdowns.

Auburn (2-1, 0-1), which needed overtime to avoid an upset by Jacksonville State a week earlier, trailed 24-0 at halftime and never threatened thereafter.

(At) No. 16 Oklahoma 52, Tulsa 38: Baker Mayfield threw for 487 yards and four touchdowns and ran for another 85 yards and two scores to power the Sooners.

Mayfield set a school record with 572 total yards. Samaje Perine ran for 152 yards, Sterling Shepard caught eight passes for 144 yards and Mark Andrews caught two TD passes for the Sooners (3-0).

Tulsa (2-1) stuck with Oklahoma for much of the game with Dane Evans throwing for 427 yards and four touchdowns and Keyarris Garrett catching 14 passes for 189 yards.

Oklahoma led 31-24 at halftime. The teams combined for 863 yards in the first half, the most in a first half since Fresno State and San Jose State combined for 1,002 in a 2013 game.

The teams combined for 1,376 yards.

(At) No. 17 Texas A&M 44, Nevada 27: Kyle Allen threw four touchdown passes and ran for a score to lead the Aggies to their 19th straight nonconference victory, the longest active streak in the Football Bowl Subdivision.

Texas A&M (3-0) was up by four early in the second quarter before scoring 17 straight points, with two touchdown catches by Josh Reynolds, to make it 31-10 early in the third. The second one came soon after an interception by Donovan Wilson on the first play of the second half.

Tyler Stewart threw for 206 yards and two touchdowns for Nevada (1-2).

(At) No. 20 Arizona 77, Northern Arizona 13: Anu Solomon completed 25 of 35 passes for 285 yards and four touchdowns in a little more than a half of play, and Arizona set school records for points and total yards.

Arizona (3-0) broke the mark for points set in a 74-0 win 94 years ago over the school now known as UTEP. The Wildcats' 792 yards eclipsed the mark of 787 set against UNLV last season.

Solomon's backup, Jerrard Randall, scored on runs of 73 and 72 yards. Third-stringer Brandon Dawkins had a 43-yard TD run, and fourth-string quarterback Zach Werlinger ran 11 yards for a score.

No. 21 Utah 45, (at) Fresno State 24: Devontae Booker ran for 156 yards and two touchdowns, and Utah had two scores on special teams and one on defense.

Utah defensive tackle Stevie Tu'ikolovatu recovered a fumble by Fresno State quarterback Chason Virgil on a sack and returned it 37 yards for a touchdown to put the Utes (3-0) up 10-3 late in the first quarter.

Booker's 30-yard touchdown run made it 17-3 lead late in the second quarter and he added a 7-yard scoring run for a 21-point lead midway through the third.

(At) No. 22 Missouri 9, UConn 6: Anthony Sherrils’ last-minute interception allowed the Tigers to hold on in a game that featured four turnovers, two missed field goals and a blocked extra point.

With just a under a minute left, Sherrils picked off a pass by Connecticut backup quarterback Tim Boyle on a fourth-down, fake field goal attempt. Sherrils also forced and recovered a fumble with 4:26 left in the first half for Missouri (3-0). UConn is 2-1.

(At) No. 25 Oklahoma State 69, UTSA 14: Devante Averette scored on a 6-yard fumble return only 45 seconds in, and the Cowboys forced seven turnovers — all of them leading to points.

Mason Rudolph completed 17 of 23 passes for 280 yards and two touchdowns, and Chris Carson rushed for 104 yards and two touchdowns on 17 carries for Oklahoma State (3-0).

Blake Bogenschutz was 8-of-13 for 58 yards and a touchdown for UTSA (0-3), but also fumbled twice and threw two interceptions before he was taken out of the game late in the second quarter.

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