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Morgantown, W.Va. — A marquee matchup turned into a lopsided win for Oklahoma, and the Sooners now only have rival Oklahoma State in the way of back-to-back Big 12 titles.

Those playoffs hopes? Still a long shot for Oklahoma.

Baker Mayfield threw two touchdown passes and ran for two more scores and No. 8 Oklahoma scored four times off turnovers to beat No. 10 West Virginia 56-28 on Saturday night.

In the first meeting of Top 10 teams in the Big 12 this season. Oklahoma (9-2, 8-0 Big 12, No. 9 CFP) dominated from the start, building a 28-0 lead early in the second quarter before the Mountaineers tried a late comeback.

“It was really a good way to come out, really focused,” Oklahoma coach Bob Stoops said. “That’s how you want to start an important game on the road.”

Now the Sooners have two weeks to prepare for the 13th-ranked Cowboys. The title will be decided in Norman on Dec. 3.

“It will be exciting to be on our field playing for a Big 12 championship,” Stoops said. “It’s as good as it gets.”

West Virginia (8-2, 5-2, No. 14 CFP) was eliminated from the conference race. The Mountaineers entered the game with the league’s top scoring defense but had too many weapons to cover and made far too many miscues.

Samaje Perine ran for 160 yards and two TDs, Joe Mixon had 147 yards and a score, and Dede Westbrook had 100 yards receiving, including a 75-yard TD. After Oklahoma’s hot start, the Sooners kept the ball mostly on the ground. Mayfield finished 9 of 15 for 169 yards, all season lows.

West Virginia’s Justin Crawford rushed for 331 yards, the third-highest total in school history. Skyler Howard threw for two TDs and ran for two more scores. His 37-yard TD toss to Ka’Raun White pulled the Mountaineers within 41-28 with 10 minutes left in the game. But West Virginia got no closer.

“I thought we were ready to play,” West Virginia coach Dana Holgorsen said. “You can’t make mistakes against a good football team.”

(At) No. 1 Alabama 31, Chattanooga 3: Jalen Hurts passed for three touchdowns and rushed for 68 yards to help the Crimson Tide overcome a slow start and beat an FCS team.

With the offense struggling to get going, Alabama (11-0) spotted Chattanooga (8-3) the game’s first three points and didn’t really shake them until late in the third quarter. The defense had a more Bama-like performance, and hasn’t given up a touchdown in 13 quarters.

Hurts was 15-of-21 for 136 yards a week after torching Mississippi State for 347 yards. He had a 47-yard TD pass to Calvin Ridley and added two 1-yarders to Gehrig Dieter, including one in the final minutes that made the score look a little closer to what most expected.

Damien Harris rushed for 91 yards and a touchdown and Ridley gained 94 yards on seven catches.

Alabama wide receiver ArDarius Stewart did not play in the game, but it wasn’t clear if he’s injured.

It was a milestone win for Alabama coach Nick Saban, whose 41-5 record as the No. 1 team gives him the most of any coach. He had been tied with Ohio State’s Woody Hayes (40-4-1) and Florida State’s Bobby Bowden (40-5).

Chattanooga’s first-quarter field goal put Alabama behind for the first time since Kentucky scored the first three points on Oct. 1. The Mocs trailed just 14-3 until deep into the third quarter before Harris raced 25 yards for a touchdown.

Alejandro Bennifield completed 16 of 21 passes for 106 yards for the Mocs, who sacked Hurts three times.

No. 5 Clemson 35, (at) Wake Forest 13: Deshaun Watson rushed for two touchdowns and threw for another score, and the Tigers clinched a spot in the Atlantic Coast Conference title game.

Wayne Gallman rushed for a season-high 161 yards and two touchdowns, including a 42-yarder on fourth-and-inches that started the scoring for Clemson (10-1, 7-1, No. 4 CFP).

Playing with something to prove after a last-second loss to Pittsburgh was its first in the regular season in nearly two full years, Clemson reeled off touchdowns on its first four possessions to take a 28-0 lead and then essentially went into protection mode while holding the Demon Deacons to 197 yards — its fewest since the opener against Tulane.

One mitigating factor: A persistent northerly wind that gusted at nearly 30 mph. Clemson’s starters scored four of their five touchdowns with the wind at their backs, but had just 185 total yards in the second and third quarters — when those gusts were in their faces.

Watson was 23-of-33 for 202 yards and sandwiched a pair of short scoring runs around a pretty 15-yard touchdown pass to Mike Williams, checking out after Gallman’s second TD with 10:50 to play.

Cade Carney had a 1-yard touchdown run and Mike Weaver kicked field goals of 42 and 23 yards for Wake Forest (6-5, 3-4).

(At) No. 7 Washington 44, Arizona State 18: Jake Browning overcame a sluggish start to throw for 338 yards and two touchdowns, and the Huskies routed the Sun Devils to stay in the College Football Playoff mix.

Washington (10-1, 7-1 Pac-12) likely will move up in both the AP Top 25 and the CFP ranking after snapping a 10-game losing streak to Arizona State. But the Huskies appeared to let last week’s loss to Southern California linger early before a 21-point second quarter put them fully in control.

Browning completed 27 of 44 passes with 12 of those going to John Ross for 95 yards. Myles Gaskin ran for 127 yards and a 45-yard touchdown in the fourth quarter.

Washington’s victory sets up one of the biggest Apple Cup’s ever Friday in Pullman against Washington State with the winner claiming the Pac-12 North title and a spot in the conference title game. The two are tied on top of the North Division standings after Washington State’s loss at Colorado.

Washington’s defense dominated from the outset, holding Arizona State (5-6, 2-6) to 48 yards in the first half and just 84 through three quarters before reserves took over. Arizona State’s Manny Wilkins was 20-of-32 passing for 227 yards but was sacked six times. N’Keal Harry had six catches for 114 yards, but the Sun Devils managed only 15 yards rushing.

Jay Jay Wilson had Arizona State’s only touchdowns, catching a pair of fourth-down TDs in the fourth quarter. And if the night needed to be any wackier, Washington linebacker Keishawn Bierria scooped up an onside kick attempt and returned it for a touchdown with 6:03 remaining.

Oregon 30, (at) No. 11 Utah 28: Justin Herbert hit Darren Carrington for a 17-yard touchdown pass with two seconds remaining to give the Ducks the upset victory and put the Utes’ hopes of a Pac-12 championship in jeopardy.

Herbert led Oregon, which has struggled all season and suffered several lopsided losses, on a 10-play, 75-yard drive in just over two minutes, capping it with the TD pass to Carrington. Carrington was initially called out of bounds but that call was reversed after a replay showed he got a foot down inbounds.

Herbert finished the game with 324 yards passing and three TDs. He also scored on a 1-yard run in the fourth quarter.

Utah had taken a 28-24 lead with 2:18 remaining off a Troy Williams 30-yard touchdown pass, but the Ducks then began their comeback drive.

Royce Freeman led the Ducks ground game with 129 yards. He also scored on a 1-yard pass from Herbert early in the fourth.

Joe Williams rushed for 149 yards and a touchdown for Utah. The normally stout Utes defense gave up 575 yards of offense to Oregon.

Utah led 7-3 at halftime as both teams had several miscues in important moments.

The Ducks drove inside the Utah 40-yard line on all five first-half possessions, but came away with just three points. They failed to convert on fourth down on their first possession of the game and missed a 41-yard field late in the second quarter.

(At) No. 12 Colorado 38, No. 20 Washington State 24: Sefo Liufau threw for 345 yards, rushed for 108 more and scored three touchdowns as the Buffaloes beat the Cougars in a matchup of unlikely Pac-12 division leaders.

Phillip Lindsay added 144 yards rushing and two TDs for Colorado (9-2, 7-1, No. 10 CFP), who could wrap up the South side of the conference if Southern California were to lose to UCLA later Saturday or by beating Utah next week.

Liufau briefly left in the fourth quarter only to return and pick up a crucial third-and-short that led to a game-sealing TD run by Lindsay.

Luke Falk threw for 325 yards and three scores for Washington State (8-3, 7-1, No. 22 CFP), which had won eight in a row. The Cougars can still win the North Division with a victory against No. 7 Washington next week.

The Colorado defense did its part, too, with Jimmie Gilbert forcing Falk to fumble with around 3 minutes remaining and Addison Gillam pouncing on it.

Mike Leach’s gambling mentality cost the Cougars a possible field goal when he went for it on fourth-and-4 in the fourth quarter. Colorado safety Nick Fisher tackled receiver Kyle Sweet short of the first down.

Earlier, Leach rolled the dice on fourth-and-1 at his own 41 and Jamal Morrow rewarded his faith by gaining 30 yards. John Thompson later hauled in a 7-yard TD pass to give the Cougars a 24-21 lead.

The Cougars finished 2-of-4 on fourth-down attempts.

No. 13 Oklahoma State 31, (at) TCU 6: Mason Rudolph ran for two touchdowns and threw for another score and the Cowboys earned a Big 12 title shot with their seventh consecutive victory.

Oklahoma State (9-2, 7-1, No. 11 CFP) will be conference champion if it beats No. 8 Oklahoma in the regular-season finale after an open date.

The Cowboys scored on their only two drives in the third quarter to go ahead 24-6. Chris Carson had a bruising 19-yard TD run when he got through three tacklers and Rudolph scored on a 2-yard keeper immediately after a 63-yard catch-and-run by Chris Lacy.

TCU (5-5, 3-4) had a chance to take the lead in the final minute of the first half after a 40-yard run by quarterback Kenny Hill. But Kyle Hicks took direct snaps in a wildcat formation on consecutive plays from the 1, getting stopped short on a third-down run and then overthrowing an open receiver.

Justice Hill had 154 yards rushing on 16 carries for Oklahoma State, and Carson had 146 yards on 17 carries. Lacy had four catches for 109 yards.

No. 15 USC 36, UCLA 14: Sam Darnold passed for 267 yards and hit De'Quan Hampton for two touchdowns, leading Southern California in the Los Angeles rivals' 86th crosstown showdown.

Ronald Jones II rushed for 121 yards and two TDs for the surging Trojans (8-3, 7-2 Pac-12), who won their seventh straight game after a dismal start to the season.

USC claimed the Victory Bell for the second consecutive year, overcoming Darnold's two early interceptions and eventually taking apart UCLA's solid defense for 527 total yards.

Jordan Lasley caught two first-half touchdown passes from Mike Fafaul for UCLA (4-7, 2-6). After five losses in their last six games, the Bruins are assured their first losing season in coach Jim Mora's half-decade in charge.

No. 21 Florida 16, (at) No. 16 LSU 10: Florida stuffed LSU’s Derrius Guice on a do-or-die run from the 1 in the final seconds and the Gators held on to wrap up the Southeastern Conference’s East Division title.

The stop capped a defensive struggle in which LSU converted a fourth-and-10 play on its final drive, only to get stopped on back-to-back runs from the 1 to end the game.

Florida’s Austin Appleby completed only seven passes on 17 attempts, but one of his connections went for a pivotal 98-yard touchdown to Tyrie Cleveland. Eddy Piniero scored the rest of Florida’s points on field goals of 36, 24 and 34 yards.

LSU (6-4, 4-3 SEC, No. 16 CFP) controlled most of the game and held considerable statistical advantages, outgaining Florida (8-2, 6-2, No. 23 CFP), 423 yards to 270 and holding possession for 34:02. But on three occasions, the Tigers failed to score after driving inside Florida’s 10 — the first time because of Guice’s fumble in the first half and the second time because of a botched field goal in the third quarter. The loss likely cost the Tigers a Sugar Bowl bid.

No. 17 Florida State 45, (at) Syracuse 14: Dalvin Cook ran for 225 yards and four touchdowns to become the Seminoles’ career rushing leader.

Cook entered the game needing 19 yards to break Warrick Dunn’s 20-year-old school record for rushing (3,959) and did so with a 41-yarder in the first quarter. He finished the first half with 104 yards to become just the sixth player in Atlantic Coast Conference history to reach 4,000 yards and the first to do it in three years.

Florida State (8-3, 5-3, No. 17 CFP) won for the fifth time in six games and handed Syracuse (4-7, 2-5) its third straight loss.

Syracuse starting quarterback Eric Dungey again warmed up before the opening kickoff but did not play for the second straight game. The sophomore has been out since suffering a vicious hit to the shoulder-head area in the first quarter against Clemson two weeks ago.

Backup Zack Mahoney had trouble generating any consistency on offense against the Seminoles defense. Florida State intercepted two passes, registered eight sacks, and forced 10 punts in limiting Syracuse to 3.2 yards per play. FSU averaged 8.6 yards per play.

Mahoney finished 16-of-36 for 196 yards, but he did have one lucky strike. He hit Amba Etta-Tawo with a 46-yard Hail Mary on the final play of the first half. Etta-Tawo caught the ball in double coverage at the right corner of the end zone.

If Syracuse had hopes the big play would provide a spark, Cook dashed those hopes with three touchdowns in the third.

After tight end Ryan Izzo’s 39-yard reception on the first possession of the third quarter, Cook scored on an 11-yard run and added two more scores in the period, from 11 and 17 yards. That matched his career high for TDs in a game and boosted his season total to 18.

(At) No. 18 Auburn 55, Alabama A&M 0: Jeremy Johnson accounted for three touchdowns, and the Tigers made the most of their final tuneup before the Iron Bowl.

Starting in place of the injured Sean White, Johnson was 14-of-19 for 147 yards and a touchdown and rushed for two more for Auburn. It was Johnson’s first start of the season and the first game he received substantial playing time since the opener against Clemson, and he led the charge for a wire-to-wire win on Senior Day.

Kerryon Johnson ran for 108 yards and a touchdown on 18 carries before being lifted for freshman Kam Martin at halftime. Kamryn Pettway, who entered the week leading the SEC in rushing, missed his second consecutive game with a left leg injury. Among the other Tigers to sit out the final home game of the season were running back Stanton Truitt, H-back Chandler Cox and cornerback Carlton Davis.

Auburn (8-3, No. 15 CFP) outgained Alabama A&M (4-7), 598 yards to 130, and had its first shutout since the first game of the 2008 season.

John Franklin III ran for 81 yards and a touchdown on four carries in mop-up duty for Johnson, and Martin finished as the leading rusher with 176 yards and a pair of touchdowns — all in the second half — thanks to a few long runs.

De’Angelo Ballard was 15-of-39 for 103 yards for the Bulldogs.

(At) No. 23 Texas A&M 23, UTSA 10: Jake Hubenak threw for 248 yards and a touchdown and Myles Garrett had 41/2 sacks to help the Aggies get back on track.

Texas A&M (8-3) was in desperate need of a victory after consecutive losses to Mississippi State and Mississippi ruined its shot at the College Football Playoff.

The Roadrunners (5-6) cut the lead to three early in the second quarter after a one-handed touchdown grab by Josh Stewart. The Aggies then scored the next 13 points, capped by a 47-yard run by Trayveon Williams to make it 23-7 in the third quarter.

Garrett was finally healthy after missing two games and being limited in several others because of a high ankle sprain. He finished with eight tackles, broke up a pass and forced a fumble. Instead of limping as he has been in recent weeks, Garrett was harassing UTSA’s two quarterbacks all game.

(At) Wyoming 34, No. 24 San Diego State 33: Josh Allen threw for two touchdowns, including a 29-yard score to C.J. Johnson with 1:07 left in the game, and the Cowboys stopped a 2-point conversion attempt by the Aztecs with no time on the clock for the upset.

Allen completed 16 of 31 passes for 282 yards and also rushed for 56 yards for Wyoming (8-3, 6-1 Mountain West). Brian Hill added 131 yards on 31 carries and two TDs.

Johnson finished with five catches for 85 yards.

It was Wyoming’s second win this season over a Top 25 team. Wyoming beat then-No. 13 Boise State three weeks ago.

San Diego State (9-2, 6-1) was led by Christian Chapman, who completed 15 of 26 passes for 211 yards and two TDs. Chapman’s last TD pass was a 23-yard desperation heave that Quest Truxton caught on the rebound with no time left.

Aztecs coach Rocky Long elected to go for the win and Chapman’s 2-point conversion pass attempt was knocked away by defensive back Antonio Hull.

Rashaad Penny and Juwan Washington both returned kickoffs for touchdowns for the Aztecs. Penny’s was 93 yards, and Washington’s 92 yards.

Donnel Pumphrey, who entered the game as the nation’s leading rusher, was held to 76 yards on 17 carries. Still, Pumphrey surpassed Hall of Famer Tony Dorsett for third place on the NCAA career rushing list and now has 6,127 yards. He trails Ron Dayne, who amassed 6,397 yards at Wisconsin, and Ricky Williams, who gained 6,279 yards at Texas.

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