Washington — Top-ranked Villanova led by as many as 44 points — 44! — and gave Georgetown coach Patrick Ewing a rude welcome back to the schools’ rivalry, handing the Hoyas their worst loss in more than 40 years, 88-56, Wednesday night.

Jalen Brunson led the way with 18 points and seven assists for Villanova (17-1, 5-1 Big East), which finished 17 for 33 on 3s, while Georgetown went 4 for 15.

Mikal Bridges scored 17 for the Wildcats, winners of seven consecutive games against the Hoyas, Villanova’s longest streak in a series that dates to 1922.

The last time Ewing faced Villanova in any capacity was in the last game of his college playing career at Georgetown, a surprising 66-64 victory for the underdog Wildcats in the 1985 NCAA championship game. It was quite clear, quite quickly, on Wednesday that there would be no such tight outcome —nor any chance of an upset by Georgetown (12-6, 2-5).

This is Ewing’s first season as a head coach at any level, and he opted to go with an easy-as-can-be non-conference schedule to try to build his players’ confidence. Now that league play is underway, especially against a foe like Villanova, the gap between the Hoyas and the best teams is obvious.

More Top 25

SMU 83, (at) No. 7 Wichita State 78: Shake Milton hit five 3-pointers en route to a career-best 33 points as SMU prevailed on the road. Wichita State, which had won 27 straight.

(At) Texas 67, No. 8 Texas Tech 58: Kerwin Roach II scored 20 points in a surprise return to the lineup and Texas got another home win over a Top 25 opponent in a week.

(At) No. 11 Xavier 88, St. John's 82: Kerem Kanter had 22 points and led a late run that swept Xavier to a victory over St. John’s that gave Chris Mack the Musketeers record for career coaching wins.

No. 14 Arizona 79, (at) California 58: Deandre Ayton had 20 points and 11 rebounds, and Arizona overcame a slow, sloppy start to beat California.

(At) Alabama 76, No. 17 Auburn 71: John Petty scored 27 points, Dazon Ingram added 16, and short-handed Alabama defeated the visitors.

(At) Creighton 80, No. 19 Seton Hall 63: Marcus Foster scored 25 points and reserve Ronnie Harrell Jr. had a career-high 18, and Creighton never trailed against Seton Hall.

(At) Missouri 59, No. 21 Tennessee 55: Kevin Puryear had 12 points and 10 rebounds, and Missouri rallied in the second half to beat Tennessee.

(At) No. 24 TCU 96, Iowa State 73: Vladimir Brodziansky had 26 points and TCU snapped a three-game losing streak with a victory over Iowa State while playing for the first time without injured starting point guard Jaylen Fisher.

Big Ten

No. 22 Ohio State 71, (at) Northwestern 65: Chris Holtmann became the first coach in 95 years to win his first seven Big Ten games as C.J. Jackson had 12 points, eight assists and three steals for the Buckeyes (16-4, 7-0 Big Ten), who won their sixth straight overall. Vic Law scored 14 points and Scottie Lindsey added 13 for Northwestern (11-9, 2-5).

(At) Rutgers 80, Iowa 64: Corey Sanders had 18 points and eight assists and two steals and Geo Baker had 17 points, five rebounds, five assists and two steals, to lead Rutgers on Wednesday night.

State women

Central Michigan 81 (at) Northern Illinois 78: The 28 points the visitors racked up in the third quarter proved the difference. Reyna Frost scored 19 points to lead CMU (13-3 and 5-0 in the MAC).

(At) Eastern Michigan 69 (OT), Western Michigan 67: Danielle Minott led Eastern (8-9, 4-2 MAC) with 29 points while Sasha Dailey added 16 and  Emoni Jackson had 13.  Breanna Mobley had 21 points for Western (10-8, 3-3 MAC).