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Bob Wojnowski and John Niyo preview the Michigan State-Ohio State and Michigan-Iowa games on this week's "The Detroit News' College Football Show." The Detroit News

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Matt Charboneau, Angelique S. Chengelis, John Niyo and Bob Wojnowski of The Detroit News offer their predictions on the outcome of Saturday’s Michigan State vs. Ohio State game at Ohio Stadium in Columbus (7:30, ABC/760).

►Matt Charboneau: The Spartans feel like they’ve finally started to find a rhythm on the offensive side of the ball, but after giving up 31 points last week to Indiana, there are sudden questions about the defense. How much any of it matters this week at Ohio State remains to be seen as the Buckeyes have been dominant on both sides of the ball. It’s true the Buckeyes haven’t played a daunting schedule and the Spartans likely will be their toughest test yet, but it’s hard to see Michigan State having the playmakers to pull off an upset in a stadium where it’s had its share. Ohio State 34, Michigan State 17

►Angelique S. Chengelis: This seems more about Ohio State than it does Michigan State. The Buckeyes are clicking in every way, look like a national championship contender, and they’re playing at home at night. Yes, Michigan State has had some success against the Buckeyes as Mark Dantonio has led the Spartans to three Big Ten championships, twice upsetting Ohio State along the way. Dantonio said this week that you have to measure up to Ohio State if you’re going to go places in the Big Ten and beyond, but it just doesn’t look like any Big Ten team measures up to the Buckeyes right now. There's no doubt Dantonio will have the Spartans motivated for this one, but this time, that's just not going to be enough. Ohio State 38, Michigan State 10

►John Niyo: No opponent has fared better in Columbus over the years than the Spartans. But while Michigan State's offense has made some strides the last few weeks, Ohio State's defense, led by Chase Young, is a different animal. Ohio State 41, Michigan State 17

►Bob Wojnowski: The Spartans know the routine, huge underdogs in Columbus, nobody expecting them to win. Mark Dantonio has pulled it off before, and to have a chance again, he needs his defense to be more than very good. He needs it to wreak havoc, hit QB Justin Fields, knock the ball loose. The Spartans showed cracks last week and the Buckeyes turn cracks into craters. Fields has 16 touchdowns and no interceptions, although the Buckeyes haven’t faced anybody tough yet. Michigan State has the formula but not the depth of talent. Ohio State 38, Michigan State 13