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East Rutherford, N.J. — The wait for Saquon Barkley may finally be over for the New York Giants.

The 2018 NFL Offensive Rookie of the Year was a full-go at practice Wednesday, increasing the likelihood he will play against the Arizona Cardinals (2-3-1) this weekend. 

It will be the first time the running back has played since sustaining a high sprain to his right ankle on Sept. 22 against Tampa Bay Buccaneers.

Coach Pat Shurmur said the team would watch Barkley in practice the rest of the week before determining whether he will play.

The Giants (2-4) also might get tight end Evan Engram back Sunday. He also practiced fully Wednesday and said he ran and cut on his injured knee without any problem.

The offense has struggled in recent losses to Minnesota and New England, averaging 212 yards. Barkley, Engram, top wide receiver Sterling Shepard and backup running back Wayne Gallman missed the game against the undefeated Patriots.

While they are only a game behind Dallas and Philadelphia (3-3) in the NFC East, quarterback Daniel Jones said the team needs to get back on track.

“I think we’re always going to feel the urgency to fix things we haven’t done as well,” Jones said. “To improve, I think that should always be there.”

The game will feature Jones, the No. 6 overall pick in the draft, against Cardinals rookie Kyler Murray, the top pick.

The Giants have scored 24 points in the past two games.

Barkley, the No. 2 overall pick in last year’s draft, adds a dimension to the offense with his ability to run and catch passes. 

He had 37 carries for 237 yards (a 6.4 yard average) before being hurt late in the first half against the Bucs. 

Domestic violence alleged

Raiders tackle Trent Brown has been sued by his ex-girlfriend for what she says were multiple acts of domestic violence over the past year.

Diorra Marzette-Sanders filed a civil suit in Alameda County Superior Court on Tuesday accusing him of several attacks that left her bloodied, bruised and fearing for her safety.

According to the lawsuit, Marzette-Sanders accused the 6-foot-8, 380-pound Brown of slapping her, hitting her and choking her at different times and threatening to shoot her in the “head before you walk out that door with my son.”

Brown denied the accusations.

Dolphins tap Fitzpatrick

Ryan Fitzpatrick will start ahead of Josh Rosen for Miami in this Sunday’s game against the Buffalo Bills (4-1), Dolphins coach Brian Flores said.

Fitzpatrick says this season has been a “roller-coaster” but he is excited to get his second chance to lead the Dolphins. 

His promotion comes on the heels of almost leading Miami to a comeback win during the fourth quarter of last Sunday’s loss to Washington (1-5).

A failed two-point conversion ultimately led to Miami’s fifth straight loss this season, keeping the Dolphins in prime position to land the No. 1 overall pick in the 2020 NFL draft. 

But the Dolphins (0-5) are looking to score their first victory of the Flores era.

Tannehill to start

The Tennessee Titans want to jump-start an offense that has just one touchdown over the past 10 quarters, so they’re turning to veteran quarterback Ryan Tannehill and benching Marcus Mariota. At least for Sunday.

“We’re trying to get a little spark, trying to evaluate what we’re doing and how we’re functioning as an offense,” coach Mike Vrabel said.

Tannehill, the eight-year veteran with 88 career starts for Miami, will make his first Tennessee start against the Chargers (2-4).

Parting shot

Jaguars defensive tackle Marcell Dareus grabbed his lower back, feigning pain and a limp, as he left the locker room. “Oh, my back,” Dareus joked, taking a not-so-subtle shot at newly departed cornerback Jalen Ramsey.

It was the most negative thing the Jaguars (2-4) said publicly about their former teammate. Privately, though, several guys expressed relief that the monthlong saga was over.

Jacksonville traded Ramsey to the Rams on Tuesday for three draft picks, including two first-rounders.

Extra points

Browns defensive end Myles Garrett said he was punched in the face by a “fan” who wanted to take a picture with him. Garrett posted on his Twitter account that the person “hopped” out of his car before delivering a blow that had little effect.

... Bears are cautiously optimistic quarterback Mitchell Trubisky (left shoulder) will return from a left shoulder injury this week against the Saints.

... The Raiders signed tight end Darren Waller to a multiyear contract extension.

... Steelers quarterback Mason Rudolph will return to the starting lineup when he is cleared to return from a concussion sustained against Baltimore on Oct. 6. Pittsburgh is off this week.

... Rams safety John Johnson (shoulder) has been placed on injured reserve.

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