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Green Bay, Wis. -- Lions right guard Larry Warford exited in the second quarter with a knee injury and did not return Sunday against the Packers.

After suffering the injury, Warford took a cart to the locker room and had a towel on his head, a sign that it could be something serious.

Coach Jim Caldwell didn't provide an update after the game and said he was "not sure" if Warford would be available for next week's playoff game against the Cowboys.

"Larry is a guy that we're hoping heals quickly, but we'll see how that goes," he said.

Warford missed three games earlier this season with a left knee injury, and trainers appeared to be looking at his left knee before he got on a cart Sunday.

Warford suffered the injury when the Lions went for a fourth-and-10 with 6:24 left in the second quarter. Matthew Stafford's pass sailed over Golden Tate's head, resulting in a turnover on downs. With Warford out, veteran Garrett Reynolds filled in at right guard.