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Allen Park — In seven NFL seasons, Lions free safety Glover Quin has missed only one game, sitting Week 13 of his rookie year with the Texans due to a concussion.

Now, after starting 98 straight games, another brain injury is putting Quin at risk of losing his ironman title among NFL safeties.

For Sunday’s game against the 49ers (1 p.m., FOX), Quin is among seven starters listed as questionable, the same designation he’s had since suffering an ankle injury against the Eagles on Thanksgiving.

Quin returned to practice Friday, creating a possibility that he’ll recover from the concussion before Sunday’s game, but he has to pass the league’s concussion protocol in order to keep his streak going.

“I was telling people, like, man, ‘Everything’s trying to happen to stop me from getting to 100, you know?’” Quin said Friday. “I definitely don’t put a streak ahead of my health, obviously. I’ve got hopefully a long life to live with a nice family and kids and wife, so I definitely won’t be that selfish.

“But if I’m feeling good enough to play, I’ll play, and it would mean a lot to me to get to 100.”

Quin missed practice Wednesday and Thursday and was limited Friday.

“We’ll see,” coach Jim Caldwell said Friday of Quin’s availability. “He’s coming along.”

Wide receiver Calvin Johnson (ankle), defensive tackles Haloti Ngata (neck) and Caraun Reid (ankle), right tackle Michael Ola (knee), right guard Larry Warford (quad) and linebacker Josh Bynes are questionable after being limited all three days this week.

Cornerback Bill Bentley (illness) also returned to practice in full Friday after sitting out Thursday, and he’s questionable.

If Quin can’t play Sunday, Isa Abdul-Quddus and James Ihedigbo will be the starting safeties. The tandem played fine in the two games Quin exited with injuries, last Monday and on Thanksgiving against the Eagles.

“I’m anticipating that there won’t be any difference (in our defense) other than the fact, obviously, that we’re missing a Pro Bowl player in there,” Caldwell said. “Other than that, we’re not going to change schematically.”

jkatzenstein@detroitnews.com

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