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Detroit -- As expected, DeAndre Levy will not suit up for the Detroit Lions' home opener against the Tennessee Titans. The veteran linebacker, who played all 70 defensive snaps last week, missed all three practices this week with a quad injury and is inactive on Sunday. He had been listed as doubtful on Friday's injury report.

Levy has struggled with durability the past 13 months. He suffered a hip injury during training camp last year, which essentially sidelined him the 2015 season. He started training camp this year on the physically unable to perform list with an unrelated injury, missing more than two weeks of practice time.

Fifth-round draft pick Antwione Williams is expected to start the game in place of Levy with recent waiver claim, Thurston Armbrister, working as the team's primary backup and defensive end Brandon Copeland serving as an emergency option for the position group.

Also out for the Lions are tight end Cole Wick (shoulder) and cornerback Adairius Barnes (ankle). The two rookies both missed practice time this week. Wick's injury clears the way for Orson Charles' addition to the active roster after he was inactive for the team's Week 1 victory over the Indianapolis Colts.

The final four inactives are repeat healthy scratches from last week, with guard Joe Dahl, offensive tackle Cornelius Lucas, defensive end Anthony Zettel and running back Zach Zenner not dressing against the Titans.

For Tennessee, wide receiver Kendall Wright and linebacker Derrick Morgan are both inactive. The two had been ruled out by the team earlier in the week.