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Longtime Lions general manager Matt Millen, now a TV analyst again, will miss the rest of the 2018 college football season as he continues to battle a rare and life-threatening medical condition.

The Big Ten Network released a statement Wednesday.

“We will certainly miss seeing Matt this fall, but his health is the clear priority for everyone involved and we plan to support him in any way possible,” said Mark Hulsey, senior vice president of production and executive producer at BTN, said in the statement.

Millen, 60, has battled amyloidosis since 2011. It's a disease that can lead to life-threatening organ failure.

Millen has said he eventually will need a heart transplant. Earlier this year, Millen said his heart was operating at about 30 percent.

Following his 12-year playing career, Millen moved to the broadcast booth until he was hired by the Lions to run the franchise in 2001. His seven-year tenure was not good, resulting in a 31-84 record. He was fired early in the 2008 season.

He has been calling games on BTN since 2015. He worked five games this season, alongside broadcast partner Kevin Kugler.