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Detroit — An uphill climb got a little steeper 90 minutes before kickoff when the Detroit Lions ruled out Pro Bowl cornerback Darius Slay for Sunday's game against Kansas City. 

Slay, who suffered a hamstring injury in last week's win over the Philadelphia Eagles, had been extremely limited during the practice week. After testing the injured leg during warmups, he was ultimately deemed unable to go for the matchup between unbeatens. 

That leaves the Lions to rely heavily on Mike Ford, a second-year man who finished out the game for Slay last week and started four contests as a rookie a year ago. That's not ideal against Kansas City, who possess the league's most-potent passing attack run by reigning MVP, quarterback Patrick Mahomes. 

Also out for the Lions are wide receiver Danny Amendola, defensive tackles Da'Shawn Hand and Mike Daniels, offensive tackle Oday Aboushi, guard Beau Benzschawel and running back Paul Perkins. 

Amendola (chest) and Hand (elbow) had both been listed as questionable for the contest. The veteran wide receiver was injured in the closing minutes against the Eagles while making a diving catch near the sideline. Hand has been sidelined since early in the training camp. 

The Lions promoted wide receiver Tom Kennedy off the practice squad earlier this week in anticipation of Amendola's absence. Undrafted rookie Kevin Strong is expected to pick up the slack while Daniels and Hand are out.